09:00
- 11:10
14 November
Life at the molecular level
first session
Cellular biology is a consequence of molecular interactions and chemical transformations. With the unprecedented pace of technological development, we can now look into life and understand it on the level of individual molecules. In this session, we will present the development and applications of molecular tools and methodology to study and alter biological processes. From groundbreaking nanometer imaging (e.g., ultra-super resolution fluorescent imaging MINFLUX) to sub-nanometer structural approaches (macromolecular crystallography and cryo-EM) to the development of new bioactive molecules and therapeutic and diagnostic approaches.
CHAIR
Jacek Kolanowski
SPEAKERS
Jonas Ries
– 9:00
Superresolution microscopy for structural cell biology
Magda Konarska
– 9:40
Quality control by the spliceosome and its unexpected consequences for the cell
Sebastian Glatt
– 10:05
tRNAslational control of eukaryotic gene expression
Maksim Serdakov
– 10:30
Dynamic assembly of RNA targeting complexes in bacteria
Marta Szabat
– 10:50
RNA G-quadruplexes – noncanonical structures from the influenza A virus genome
11:40
- 13:50
14 November
Life at the single cell level
second session
Recent technology advances have enabled unprecedented studies of life at single cell resolution. This session will bring together researchers who address biological questions by applying single cell techniques, from classic flow cytometry to novel sequencing approaches, to understand the complexity of life at the fundamental level.
CHAIR
Paulina Jackowiak
SPEAKERS
Nikolaus Rajewsky
– 11:40
Single Cell Resolution Omics & Artificial Intelligence for Personalized Medicine
Bożena Kamińska-Kaczmarek
– 12:20
Tumor microenvironment at single-cell resolution - unraveling transcriptional and spatial heterogeneity of immune cells.
Agnieszka Chacińska
– 12:45
Protein homeostasis at the crossroads to mitochondria
Agnieszka Ciesielska
– 13:10
Enter the resolution revolution with single cell spatial transcriptomics
Paweł Świtoński
– 13:30
Isolating Purkinje Cell Nuclei: A Gateway to Understanding SCA7 Pathology
14:50
- 17:00
14 November
Life at the organismal level
third session
Evolutionary tuned, functioning of an organism is based on complicated network of connections between different cell types, tissues and organs. Advance technologies, including various -omics approaches and live imaging, help us to tackle this complexity. In this session we will try to address this intricacy from the whole organism perspective.
CHAIR
Michał Jasiński
SPEAKERS
François Chaumont
– 14:50
Aquaporins: key ubiquitous channels for plant physiology
Ewelina Knapska
– 15:30
The Central Amygdala as a Motivational Hub: Paving the Way for Personalized Therapies in Behavioral Disorders
Wojciech Pokrzywa
– 15:55
Extracellular Vesicles in Reproductive Adaptation: A Tale of C. elegans' Response to Internal and External Stimuli.
Savani Anbalagan
– 16:20
A ligand-receptor interactome atlas of the zebrafish
Łukasz Przybył
– 16:40
New Huntington’s disease mouse models prove mutant RNA contribution to phenotype
09:00
- 11:10
15 November
Life at the population level
fourth session
Population-scale research has gained real momentum thanks to the use of high-throughput technologies. Population-wide data collected over the last three decades provide the basis for the recognition of many unexplored phenomena underlying lifespan, health, heredity, relationships and the evolution of entire communities. The presented session will be devoted to the use of modern technologies to understand the vision of life from the perspective of the population.
CHAIR
Luiza Handschuh
SPEAKERS
Liran Shlush
– 9:00
How molecular biology and evolution will shape the diagnostics of blood malignancies
Tomasz Grzybowski
– 9:40
Prediction of human biogeographic ancestry within Europe
Krzysztof Pyrć
– 10:05
Advanced Models for Comprehensive Understanding of Viral Infection
Piotr Ziółkowski
– 10:30
Crossover recombination from the population perspective: interplay between meiotic recombination and polymorphism in plants
Katarzyna Klonowska
– 10:50
Hidden landscape of tumorigenesis-driving mutations in Tuberous Sclerosis Complex
11:40
- 13:50
15 November
Synthetic life
fifth session
Modern nucleic acid engineering offers the tools to create synthetic genes and to rationally modify genomes and transcriptomes. This, in turn, allows the engineering of proteomes and metabolomes, and consequently enables the creation of completely new biological systems. In this session we will discuss the possibilities and limitations of synthetic biology and its impact on the progress of other fields of science.
CHAIR
Marta Olejniczak
SPEAKERS
Andrzej Dziembowski
– 11:40
Complex metabolic pathways of mRNA therapeutics
Małgorzata Borowiak
– 12:20
Mechanosignaling in the Differentiation and Expansion of Human Pancreatic Beta Cells
Marcin Drąg
– 12:45
In search of perfection - the phenomenon of unnatural amino acids
Katarzyna Tutak
– 13:10
RPS26 a novel RAN translation modifier of RNA harboring expanded CGG repeats in Fragile X-associated syndrome
Emilia Iłowska
– 13:30
Self-assembly peptides – new way in antimicrobial and anticancer research
14:50
- 17:00
15 November
Digital and virtual life
sixth session
For many years now, with the availability of increasing computing power and the development of specialized data processing and analysis techniques, the in silico approach has been gaining importance. Nowdays it is broadly used to describe, model, simulate and visualize biological and medical processes, and it is a fundation of computational biology and computational biomedicine. The goal of research in these areas is to provide high-fidelity descriptions and predictions of the behavior of complex biological and biomedical systems. They are of fundamental scientific value and directly imply the emergence of innovative IT solutions that provide important support for clinicians in making diagnostic decisions in the face of ever-increasing amounts of available data.
CHAIR
Tomasz Piontek
SPEAKERS
Rossen Apostolov
– 14:50
HPC for Life Science Research: Advanced Applications for Extreme-scale Biomolecular Simulations
Aleksandra Pękowska
– 15:30
Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to brain evolution.
Cezary Kępka
– 15:55
Jacek Kwieciński
– 15:55
AI support in diagnosis and treatment of complicate cardiovascular patients
Mariusz Kruk
– 15:55
Advanced post-processing of coronary computed tomography images - benefits for patients and health professionals.
Derek Groen
– 16:20
Simulating conflict-driven population displacement using large-scale computing
Alexander Zelenka Martin
– 16:40
Hybrid algorithms on a photonic quantum processor